Even the generic pills aren't cheap anymore: There was no drug shortage, according to the Food and Drug Administration, that might explain the [price] increase. There was no new patent or new formulation. Digoxin is not hard to make. What had changed most were the financial rewards of selling an ancient, lifesaving drug and company strategies intended to reap the benefits.
A fun and poetic quality of the American healthcare story is how, even as it gets better, it keeps getting worse: Every sideways step around treatable sickness is nonetheless a forward step closer to death.