Friday, November 4th, 2011
5

If You Give A Mouse Cocaine You Should Probably Give Him A Cigarette First

"Nicotine causes changes in gene regulation that enhance the brain's subsequent response to cocaine. The finding, in mice, provides the first clear evidence for a molecular mechanism supporting the idea of 'gateway drugs'…. In a study published today in Science Translational Medicine, the team shows that, in mice at least, nicotine causes epigenetic changes–long-lasting changes in the control of gene expression–that subsequently boost the response to cocaine."

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5 Comments / Post A Comment

camelface (#4,600)

Wait a second. You can “enhance the brains response to cocaine?” Dan Savage was right! It DOES get better!

Multiphasic (#411)

I was going to pshaw this, but it's the Kandels, and you can't really fuck with them.

BadUncle (#153)

I'm going long on snuff stocks.

johnpseudonym (#1,452)

So cocaine would be even better if I smoked?

scrooge (#2,697)

Another example of institutional bias against tobacco. If they'd been objective, they would also have tested whether having cocaine made you (or a mouse) more likely to smoke.

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